Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28776906 | 0.86 | TDP1 (0.53) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4964088 | 0.81 | TDP1 (0.57) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9556010 | 0.81 | TDP1 (0.57) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2299148 | 0.76 | PKM (0.50) | TDP1KDM4EALDH1A1CYP3A4ALOX15 | |
| SCHEMBL13365083 | 0.76 | ALDH1A1 (0.60) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29112021 | 0.76 | PKM (0.46) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2427891 | 0.76 | ALDH1A1 (0.56) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL561310 | 0.76 | PKM (0.50) | TDP1KDM4EALDH1A1CYP3A4ALOX15 | |
| SCHEMBL8671212 | 0.76 | TSHR (0.59) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL3478112 | 0.76 | TSHR (0.59) | TDP1MEN1KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011323-A | ANTIOBESITY AND ANTIDIABETIC | SANDOZ, INC. (US) | 1977-03-08 | — | — | US | disclosed |