Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.57 |
| ▸ | PPARA | Q07869 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TERT | O14746 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 3/20 | 0.56 |
| ▸ | F7 | P08709 | 3/20 | 0.56 |
| ▸ | F3 | P13726 | 3/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549553 | 1.00 | PPARG (0.57) | PPARGPPARAMAPTTERTPTPN1 | |
| SCHEMBL3017777 | 1.00 | PPARG (0.57) | PPARGPPARAMAPTTERTPTPN1 | |
| SCHEMBL17334530 | 0.92 | PPARG (0.48) | PPARGPPARAMAPTTERTPTPN1 | |
| SCHEMBL29626440 | 0.88 | HCAR2 (0.55) | PPARGPPARAMAPTLMNAALDH1A1 | |
| SCHEMBL31681514 | 0.88 | HCAR2 (0.55) | PPARGPPARAMAPTLMNAALDH1A1 | |
| SCHEMBL23647596 | 0.85 | ALDH1A1 (0.65) | PPARGPPARAHSD17B10LMNAPOLB | |
| SCHEMBL23073887 | 0.85 | ALDH1A1 (0.65) | PPARGPPARAHSD17B10LMNAPOLB | |
| SCHEMBL23777270 | 0.85 | ALDH1A1 (0.65) | PPARGPPARAHSD17B10LMNAPOLB | |
| SCHEMBL21489709 | 0.85 | ALDH1A1 (0.65) | PPARGPPARAHSD17B10LMNAPOLB | |
| SCHEMBL21489710 | 0.85 | ALDH1A1 (0.65) | PPARGPPARAHSD17B10LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052423-A | FROM A VINYLMERCURIC HALIDE, CARBON MONOXIDE AND ALCOHOL | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1977-10-04 | — | — | US | disclosed |