Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | F7 | P08709 | 3/20 | 0.48 |
| ▸ | F3 | P13726 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745554 | 0.92 | PPARG (0.57) | PPARGPPARAPPARDTOP1CYP19A1 | |
| SCHEMBL3017777 | 0.92 | PPARG (0.57) | PPARGPPARAPPARDTOP1CYP19A1 | |
| SCHEMBL28549553 | 0.92 | PPARG (0.57) | PPARGPPARAPPARDTOP1CYP19A1 | |
| SCHEMBL28645015 | 0.88 | HCAR2 (0.50) | PPARGPPARAPPARDTOP1CYP19A1 | |
| SCHEMBL10534314 | 0.88 | HCAR2 (0.50) | PPARGPPARAPPARDTOP1CYP19A1 | |
| SCHEMBL46377 | 0.88 | HCAR2 (0.50) | PPARGPPARAPPARDTOP1CYP19A1 | |
| SCHEMBL29626505 | 0.85 | HCAR2 (0.57) | KMT2AALDH1A1MAPTHSD17B10LMNA | |
| SCHEMBL28401213 | 0.84 | TSHR (0.54) | ALDH1A1ADORA3OXER1MAPTLMNA | |
| SCHEMBL12694289 | 0.84 | TSHR (0.54) | ALDH1A1ADORA3OXER1MAPTLMNA | |
| SCHEMBL29626440 | 0.83 | HCAR2 (0.55) | PPARGPPARAALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896702-B2 | Methods, reagents and cells for biosynthesizing compounds | INVISTA NORTH AMERICA S.A.R.L. (US) | 2018-02-20 | — | — | US | claimed |
| EP-3155106-A2 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUND | Invista Technologies S.à.r.l. (CH) | 2017-04-19 | — | — | EP | claimed |
| WO-2015195611-A2 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUND | INVISTA TECHNOLOGIES S.À.R.L. (CH) | 2015-12-23 | — | — | WO | claimed |
| US-20150361458-A1 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUND | INV NYLON CHEMICALS AMERICAS, LLC | 2015-12-17 | — | — | US | claimed |
| US-9896702-B2 | Methods, reagents and cells for biosynthesizing compounds | INVISTA NORTH AMERICA S.A.R.L. (US) | 2018-02-20 | — | — | US | disclosed |
| EP-3155106-A2 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUND | Invista Technologies S.à.r.l. (CH) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015195611-A2 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUND | INVISTA TECHNOLOGIES S.À.R.L. (CH) | 2015-12-23 | — | — | WO | disclosed |
| US-20150361458-A1 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUND | INV NYLON CHEMICALS AMERICAS, LLC | 2015-12-17 | — | — | US | disclosed |