Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119047 | 0.91 | TDP1 (0.46) | SMN1; SMN2KDM4ECDYLLMNACYP1A2 | |
| SCHEMBL11652998 | 0.88 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4ECDYLLMNACYP1A2 | |
| SCHEMBL11745632 | 0.85 | GFER (0.44) | SMN1; SMN2KDM4ECDYLLMNACYP1A2 | |
| SCHEMBL17858617 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4ELMNACYP1A2CYP2D6 | |
| SCHEMBL9331718 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2KDM4ECDYLLMNACYP1A2 | |
| SCHEMBL11414825 | 0.81 | ALDH1A1 (0.50) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL5691122 | 0.80 | MEN1 (0.48) | SMN1; SMN2LMNACYP1A2CYP2D6MEN1 | |
| SCHEMBL11458539 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EMEN1KMT2AGAA | |
| SCHEMBL11825769 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ECDYLMEN1KMT2A | |
| SCHEMBL8035941 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014864-A | POLYESTER FIBERS | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |