Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 14/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RHEB | Q15382 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11743381 | 0.99 | CHEK2 (0.56) | CHEK2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL10348250 | 0.82 | MMP2 (0.64) | CHEK2KDM4EALDH1A1HPGDRHEB | |
| SCHEMBL11746348 | 0.82 | CHEK2 (0.53) | CHEK2KDM4ENPC1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9797307 | 0.81 | KDM4E (0.63) | CHEK2KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11744370 | 0.81 | KDM4E (0.63) | CHEK2KDM4EALDH1A1HPGD | |
| SCHEMBL14030841 | 0.78 | NR4A2 (0.55) | CHEK2KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL20034142 | 0.75 | CHEK2 (0.71) | CHEK2KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL11748575 | 0.75 | MAPT (0.54) | CHEK2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL11337480 | 0.74 | KDM4E (0.65) | CHEK2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL11132960 | 0.74 | MAPT (0.54) | ALDH1A1LMNASMN1; SMN2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001268-A | SUBSTITUTED PHENYL-BENZIMIDAZO COMPOUNDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1977-01-04 | — | — | US | disclosed |