Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 10/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RHEB | Q15382 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743141 | 0.84 | RHEB (0.67) | CHEK2NPBWR1NPC1RAB9AMAPT | |
| SCHEMBL11745692 | 0.84 | CHEK2 (0.60) | CHEK2NPBWR1NPC1RAB9AMAPT | |
| SCHEMBL28475608 | 0.82 | RAB9A (0.68) | CHEK2NPBWR1NPC1RAB9AMAPT | |
| SCHEMBL11746334 | 0.82 | CHEK2 (0.57) | CHEK2NPC1RAB9ASMN1; SMN2RHEB | |
| Hydrochloric Acid SCHEMBL11743381 | 0.81 | CHEK2 (0.56) | CHEK2NPC1RAB9ASMN1; SMN2RHEB | |
| SCHEMBL28483088 | 0.77 | NPC1 (0.71) | CHEK2NPBWR1NPC1RAB9AMAPT | |
| SCHEMBL11748575 | 0.74 | MAPT (0.54) | CHEK2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL20034142 | 0.72 | CHEK2 (0.71) | CHEK2NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28475614 | 0.72 | NPC1 (0.56) | NPBWR1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL11337480 | 0.71 | KDM4E (0.65) | CHEK2NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001268-A | SUBSTITUTED PHENYL-BENZIMIDAZO COMPOUNDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1977-01-04 | — | — | US | disclosed |