Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 12/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RHEB | Q15382 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746334 | 0.75 | CHEK2 (0.57) | CHEK2LMNASMN1; SMN2RHEBKDM4E | |
| Hydrochloric Acid SCHEMBL11743381 | 0.74 | CHEK2 (0.56) | CHEK2LMNAKMT2ASMN1; SMN2RHEB | |
| SCHEMBL11746348 | 0.74 | CHEK2 (0.53) | MAPTCHEK2LMNASMN1; SMN2RHEB | |
| SCHEMBL15793163 | 0.72 | HSPD1 (0.74) | MAPTHSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL11337480 | 0.71 | KDM4E (0.65) | MAPTCHEK2TP53LMNAMEN1 | |
| SCHEMBL516310 | 0.70 | MAPT (0.73) | MAPTHSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL15793174 | 0.70 | MAPT (0.64) | MAPTHSPD1PTPN2PTPN1PTPN5 | |
| SCHEMBL27481329 | 0.69 | TUBB4A (0.58) | MAPTPTPN1LMNAMEN1KMT2A | |
| SCHEMBL13415306 | 0.69 | SMN1; SMN2 (0.56) | MAPTKMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3919991 | 0.69 | CHEK2 (0.71) | MAPTHSPD1PTPN2PTPN1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001268-A | SUBSTITUTED PHENYL-BENZIMIDAZO COMPOUNDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1977-01-04 | — | — | US | disclosed |