Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 2/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 2/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740322 | 0.99 | PSMB1 (0.46) | PSMB1PSMB5PSMB2KDM1AHRH3 | |
| SCHEMBL11744044 | 0.99 | PSMB1 (0.46) | PSMB1PSMB5PSMB2KDM1AHRH3 | |
| SCHEMBL11740780 | 0.88 | NPC1 (0.43) | KDM1AHRH3KDM4EHRH1KCNH2 | |
| SCHEMBL11741062 | 0.86 | LTA4H (0.46) | PSMB1PSMB5PSMB2KDM1AHRH3 | |
| SCHEMBL11741581 | 0.86 | LTA4H (0.46) | PSMB1PSMB5PSMB2KDM1AHRH3 | |
| SCHEMBL11740052 | 0.86 | LTA4H (0.46) | PSMB1PSMB5PSMB2KDM1AHRH3 | |
| SCHEMBL11745312 | 0.86 | HRH3 (0.47) | KDM1AHRH3ACHEHRH1 | |
| SCHEMBL11740923 | 0.85 | ATM (0.48) | PSMB1PSMB5PSMB2KDM1AHRH3 | |
| SCHEMBL11741226 | 0.85 | HRH3 (0.47) | PSMB1PSMB5PSMB2KDM1AHRH3 | |
| SCHEMBL11744861 | 0.85 | HRH3 (0.47) | PSMB1PSMB5PSMB2KDM1AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060609-A | ANTICHOLESTEROL | MERCH PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-29 | — | — | US | disclosed |