Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746472 | 0.88 | PSMB1 (0.44) | HRH3HRH1KDM4EKDM1AKCNH2 | |
| SCHEMBL11741985 | 0.88 | FKBP1A (0.46) | NPC1RAB9AALDH1A1PKMHRH3 | |
| SCHEMBL11738901 | 0.88 | TSHR (0.49) | NPC1RAB9AALDH1A1PKMHRH3 | |
| SCHEMBL11744655 | 0.88 | ALDH1A1 (0.46) | NPC1RAB9AALDH1A1PKMHRH3 | |
| SCHEMBL11740322 | 0.87 | PSMB1 (0.46) | HRH3HRH1KDM1AKCNH2 | |
| SCHEMBL11744044 | 0.87 | PSMB1 (0.46) | HRH3HRH1KDM1AKCNH2 | |
| SCHEMBL11739808 | 0.85 | EPHX2 (0.47) | NPC1RAB9AALDH1A1PKMHRH3 | |
| SCHEMBL11742246 | 0.85 | NPC1 (0.42) | NPC1RAB9AALDH1A1PKMHRH3 | |
| SCHEMBL11740790 | 0.84 | HRH3 (0.46) | NPC1RAB9AALDH1A1PKMHRH3 | |
| SCHEMBL11739083 | 0.82 | SMN1; SMN2 (0.46) | ALDH1A1PKMHRH3HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060609-A | ANTICHOLESTEROL | MERCH PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-29 | — | — | US | disclosed |