Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755758 | 0.82 | NPSR1 (0.46) | PTGS2PTGS1KDM4EMAPTLMNA | |
| SCHEMBL11756109 | 0.82 | NPSR1 (0.46) | PTGS2PTGS1KDM4EMAPTLMNA | |
| SCHEMBL11754948 | 0.82 | PTGS2 (0.50) | PTGS2PTGS1KDM4EMAPTLMNA | |
| SCHEMBL16990923 | 0.79 | ALDH1A1 (0.62) | PTGS2PTGS1KDM4EMAPTLMNA | |
| SCHEMBL11750767 | 0.79 | NPSR1 (0.44) | PTGS2PTGS1KDM4EMAPTLMNA | |
| SCHEMBL11750516 | 0.79 | NPSR1 (0.44) | PTGS2PTGS1KDM4EMAPTLMNA | |
| SCHEMBL11747947 | 0.78 | PTGS2 (0.48) | PTGS2PTGS1KDM4EMAPTLMNA | |
| SCHEMBL11752797 | 0.78 | PTGS2 (0.48) | PTGS2PTGS1KDM4EMAPTLMNA | |
| SCHEMBL14705597 | 0.77 | KDM4E (0.53) | KDM4EMAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL11755296 | 0.76 | KDM4E (0.55) | PTGS2PTGS1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |