Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11534661 | 0.99 | DRD2 (0.53) | DRD2CCR1GAAHTR1AADRA1D | |
| SCHEMBL11537350 | 0.83 | LTA4H (0.59) | DRD2GAAHTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL11540300 | 0.82 | LTA4H (0.58) | DRD2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11755126 | 0.81 | DRD2 (0.55) | DRD2CCR1ADRA1DADRA1AADRA1B | |
| SCHEMBL3358687 | 0.79 | DRD2 (0.55) | DRD2ADRA1DADRA1AADRA1BHTT | |
| SCHEMBL11636249 | 0.77 | DRD2 (0.58) | DRD2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11536925 | 0.76 | LTA4H (0.57) | DRD2CCR1ADRA1DADRA1AADRA1B | |
| SCHEMBL11538347 | 0.76 | DRD2 (0.48) | DRD2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11538342 | 0.75 | DRD2 (0.47) | DRD2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11536473 | 0.72 | LTA4H (0.50) | DRD2CCR1HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039676-A | NEUROLEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-08-02 | — | — | US | claimed |