Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537350 | 0.82 | LTA4H (0.59) | DRD2HTTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL11540300 | 0.81 | LTA4H (0.58) | DRD2HTTADRA2AADRA2BADRA2C | |
| SCHEMBL3358687 | 0.81 | DRD2 (0.55) | DRD2HTTADRA2AADRA2BADRA2C | |
| SCHEMBL11747481 | 0.77 | DRD2 (0.54) | DRD2HTTADRA1DADRA1AADRA1B | |
| SCHEMBL11535627 | 0.77 | DRD2 (0.50) | DRD2HTTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL11534661 | 0.77 | DRD2 (0.53) | DRD2ADRA1DADRA1AADRA1BHTR1A | |
| Hydrochloric Acid SCHEMBL11536674 | 0.76 | DRD2 (0.46) | DRD2HTT | |
| SCHEMBL11755126 | 0.76 | DRD2 (0.55) | DRD2ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL11194303 | 0.76 | ADRA2A (0.54) | DRD2HTTADRA2AADRA2BADRA2C | |
| SCHEMBL11536925 | 0.75 | LTA4H (0.57) | DRD2HTTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104396-A | NEUROLEPTIC, ANALGESIC | CIBA-GEIGY CORPORATION (US) | 1978-08-01 | — | — | US | claimed |