Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.56 |
| ▸ | TYMP | P19971 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041567 | 0.85 | PPARD (0.43) | PPARAPPARDPPARGPTGS2PTGS1 | |
| SCHEMBL11753423 | 0.84 | PPARA (0.49) | PPARAPPARDPPARGPTGS2PTGS1 | |
| SCHEMBL11041560 | 0.76 | PPARD (0.49) | PPARATYMPPPARDPPARGPTGDR2 | |
| SCHEMBL11040057 | 0.75 | PTGS2 (0.48) | PPARDPTGS2PTGS1PTGDR2KDM4E | |
| SCHEMBL11041561 | 0.75 | PTGDR2 (0.45) | PPARDPTGS2PTGS1PTGDR2KDM4E | |
| SCHEMBL11040129 | 0.74 | PPARA (0.58) | PPARAPPARDPPARGPTGS2PTGS1 | |
| SCHEMBL11751327 | 0.73 | PTGDR2 (0.47) | PPARATYMPPPARDPPARGPTGS2 | |
| SCHEMBL11755821 | 0.73 | PTGDR2 (0.47) | PPARATYMPPPARDPPARGPTGS2 | |
| SCHEMBL11754318 | 0.73 | PPARD (0.48) | PPARATYMPPPARDPPARGPTGS2 | |
| SCHEMBL11753193 | 0.73 | PTGDR2 (0.50) | PPARATYMPPPARDPPARGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |