Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042394 | 0.86 | PTGS2 (0.49) | PTGDR2PTGS2PTGS1KDM4ESMN1; SMN2 | |
| SCHEMBL11753660 | 0.85 | MAPT (0.50) | PTGS2PTGS1KDM4EPOLBRAB9A | |
| SCHEMBL10801295 | 0.83 | ALDH1A1 (0.54) | PTGDR2PTGS2PTGS1KDM4EALDH1A1 | |
| SCHEMBL11754171 | 0.82 | MAPT (0.47) | PTGDR2PTGS2PTGS1KDM4ERAB9A | |
| SCHEMBL11748152 | 0.82 | MAPT (0.47) | PTGDR2PTGS2PTGS1KDM4ERAB9A | |
| SCHEMBL11041567 | 0.76 | PPARD (0.43) | PTGDR2PTGS2PTGS1KDM4ENPC1 | |
| SCHEMBL5909542 | 0.75 | KDM4E (0.49) | PTGDR2PTGS2PTGS1KDM4ENPC1 | |
| SCHEMBL11747669 | 0.75 | PPARA (0.56) | PTGDR2PTGS2PTGS1KDM4ENPC1 | |
| SCHEMBL11750815 | 0.75 | ALDH1A1 (0.50) | PTGDR2PTGS2PTGS1KDM4ESMN1; SMN2 | |
| SCHEMBL11751365 | 0.73 | L3MBTL1 (0.49) | PTGDR2KDM4EALDH1A1HPGDPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451471-A | Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |