Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.65 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16172020 | 0.85 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL16172023 | 0.83 | CHRM1 (0.61) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL11234761 | 0.83 | CHRM1 (0.65) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL18346305 | 0.81 | CHRM1 (0.63) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL16172022 | 0.80 | CHRM2 (0.57) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| 2-(Dimethylamino)Ethyl Dimethylcarbamate SCHEMBL11833151 | 0.79 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL11743007 | 0.79 | LMNA (0.44) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL3054488 | 0.77 | HCAR2 (0.39) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL9248267 | 0.77 | CHRM1 (0.58) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| 2-(Dimethylamino)Ethyl Dimethylcarbamate SCHEMBL11832882 | 0.77 | CHRNB2 (0.95) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017259-A | TERT-AMINO-N-METHYLOL, DURABLE PRESS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-04-12 | — | — | US | disclosed |