Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.63 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.63 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.63 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747716 | 0.85 | CHRNB2 (0.65) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL14433146 | 0.84 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL2822780 | 0.82 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL11234761 | 0.81 | CHRM1 (0.65) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL18346305 | 0.79 | CHRM1 (0.63) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL14005175 | 0.78 | CHRNB2 (0.38) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| 2-(Dimethylamino)Ethyl Dimethylcarbamate SCHEMBL11833151 | 0.78 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL16172023 | 0.78 | CHRM1 (0.61) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| SCHEMBL13448559 | 0.77 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 | |
| 2-(Dimethylamino)Ethyl Dimethylcarbamate SCHEMBL11832882 | 0.76 | CHRNB2 (0.95) | CHRNB2CHRNA4CHRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140308304-A1 | LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308304-A1 | LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | NPC1L1, NPC1, CETP | CHRNB2 4162/4885CHRNA4 4407/4885CHRM1 4872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.