Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753871 | 0.96 | PPARA (0.50) | PPARAPPARGCYP1A2CYP3A4MEN1 | |
| SCHEMBL11750749 | 0.92 | PPARA (0.47) | PPARAPPARGCYP1A2CYP3A4MEN1 | |
| SCHEMBL11750313 | 0.88 | SMN1; SMN2 (0.41) | PPARAPPARGMEN1KMT2ALMNA | |
| SCHEMBL11749695 | 0.87 | PPARG (0.41) | PPARAPPARGLTA4HEPHX2 | |
| SCHEMBL11753302 | 0.87 | MAOB (0.51) | PPARAPPARG | |
| SCHEMBL11745178 | 0.84 | MAPT (0.43) | PPARAPPARGCYP1A2MAPTCYP2C19 | |
| SCHEMBL11752749 | 0.84 | ALDH1A1 (0.39) | PPARAPPARGMEN1CYP2D6CYP2C19 | |
| SCHEMBL11751579 | 0.83 | KCNN4 (0.39) | PPARAPPARGCYP2C19CNR1LMNA | |
| SCHEMBL11752082 | 0.81 | PPARA (0.47) | PPARAPPARGCYP1A2CYP3A4MEN1 | |
| SCHEMBL11750958 | 0.81 | PPARA (0.38) | PPARAPPARGMEN1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051173-A | Phenoxyalkanol derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |