Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751579 | 0.96 | KCNN4 (0.39) | PPARGPPARAKCNN4 | |
| SCHEMBL11749185 | 0.92 | PPARA (0.38) | PPARGPPARAPPARDKCNN4MMP1 | |
| SCHEMBL11750313 | 0.88 | SMN1; SMN2 (0.41) | PPARGPPARAPPARDFNTAFNTB | |
| SCHEMBL11747997 | 0.87 | PPARA (0.47) | PPARGPPARALTA4HEPHX2 | |
| SCHEMBL11756569 | 0.87 | MAOB (0.51) | PPARGPPARAPPARD | |
| SCHEMBL11745178 | 0.84 | MAPT (0.43) | PPARGPPARAPPARD | |
| SCHEMBL11752749 | 0.84 | ALDH1A1 (0.39) | PPARGPPARAPPARD | |
| SCHEMBL11753871 | 0.83 | PPARA (0.50) | PPARGPPARA | |
| SCHEMBL11757005 | 0.81 | PPARG (0.40) | PPARGPPARAPPARDLTA4HEPHX2 | |
| SCHEMBL11750958 | 0.81 | PPARA (0.38) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051173-A | Phenoxyalkanol derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |