Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRG | P48443 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | VCP | P55072 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749112 | 1.00 | RXRA (0.46) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11753577 | 0.95 | MEN1 (0.40) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11752390 | 0.91 | RXRA (0.48) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11752077 | 0.88 | MEN1 (0.51) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11748931 | 0.88 | MEN1 (0.51) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11745479 | 0.84 | RXRA (0.57) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11754360 | 0.84 | RXRA (0.57) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11755317 | 0.83 | RXRA (0.44) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11753981 | 0.83 | RXRA (0.44) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL11753556 | 0.83 | NR4A2 (0.43) | RXRARXRBRXRGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |