Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670569 | 0.92 | ADRB2 (0.48) | ADRB2ADRB1ADRB3F2F7 | |
| SCHEMBL14080472 | 0.92 | ADRB2 (0.48) | ADRB2ADRB1ADRB3F2F7 | |
| SCHEMBL14080487 | 0.92 | ADRB2 (0.48) | ADRB2ADRB1ADRB3F2F7 | |
| Cadaverine Tartrate SCHEMBL14080565 | 0.88 | F2 (0.46) | ADRB2ADRB1ADRB3F2F7 | |
| SCHEMBL4012862 | 0.86 | ADRB2 (0.41) | ADRB2ADRB1ADRB3F2F7 | |
| SCHEMBL8077438 | 0.83 | FOLH1 (0.51) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL965193 | 0.82 | F2 (0.49) | ADRB2ADRB1ADRB3F2F7 | |
| SCHEMBL965192 | 0.82 | F2 (0.49) | ADRB2ADRB1ADRB3F2F7 | |
| SCHEMBL11747826 | 0.82 | ADRB2 (0.59) | ADRB2ADRB1ADRB3LMNATDP1 | |
| SCHEMBL4012485 | 0.82 | ADRB3 (0.39) | ADRB2ADRB1ADRB3F2F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021485-A | BRONCHOSPASMOLYTICS, ANTIPRURITICS, ANTIALLERGICS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-05-03 | — | — | US | disclosed |