Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755290 | 0.84 | KCNQ2 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11751326 | 0.84 | ALDH1A1 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11744599 | 0.81 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11751783 | 0.80 | MAPT (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11749353 | 0.78 | MAPT (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11748834 | 0.76 | KDM4E (0.46) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL11752276 | 0.72 | MAP2K4 (0.47) | MAPTSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL11751571 | 0.71 | CETP (0.38) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11751831 | 0.70 | PDGFRA (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11748684 | 0.70 | KCNQ2 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |