Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 5/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751236 | 0.81 | KDM4E (0.40) | KDM4EUSP2TP53MAPK1RECQL | |
| SCHEMBL11755492 | 0.77 | TSHR (0.40) | KDM4EUSP2TP53MAPK1RECQL | |
| SCHEMBL11748319 | 0.76 | GABRP (0.42) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11752876 | 0.75 | TSHR (0.47) | KDM4EMAPK1HSD17B10MAPTELANE | |
| SCHEMBL11751783 | 0.73 | MAPT (0.42) | KDM4EHSD17B10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11749353 | 0.73 | MAPT (0.42) | KDM4EMAPTALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL11751326 | 0.71 | ALDH1A1 (0.40) | KDM4EMAPK1MAPTALDH1A1TSHR | |
| SCHEMBL11755290 | 0.71 | KCNQ2 (0.42) | KDM4ETP53MAPTALDH1A1MEN1 | |
| SCHEMBL442163 | 0.70 | KMT2A (0.65) | KDM4EUSP2TP53MAPK1RECQL | |
| SCHEMBL31118653 | 0.70 | KDM4E (0.52) | KDM4EUSP2TP53MAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |