Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 4/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTR5A | P47898 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288268 | 0.70 | CREBBP (0.46) | MAPTGAAMEN1ALOX15CASP1 | |
| SCHEMBL7049313 | 0.69 | LMNA (0.38) | MAPTGAAMEN1ALOX15CASP1 | |
| SCHEMBL11085428 | 0.69 | SIGMAR1 (0.37) | MAPTGAATSHRALDH1A1KDM4E | |
| SCHEMBL29489190 | 0.69 | LMNA (0.38) | MAPTGAAMEN1ALOX15CASP1 | |
| Hydrochloric Acid SCHEMBL30920862 | 0.68 | LMNA (0.38) | MAPTGAAMEN1ALOX15CASP1 | |
| Hydrochloric Acid SCHEMBL29197876 | 0.68 | LMNA (0.38) | MAPTGAAMEN1ALOX15CASP1 | |
| SCHEMBL9365645 | 0.67 | GAA (0.43) | MAPTGAAMEN1CASP7KMT2A | |
| SCHEMBL8279432 | 0.66 | CREBBP (0.50) | MAPTGAAMEN1ALOX15CASP1 | |
| SCHEMBL6587899 | 0.66 | CREBBP (0.50) | MAPTGAAMEN1ALOX15CASP1 | |
| SCHEMBL30570964 | 0.66 | CREBBP (0.50) | MAPTGAAMEN1ALOX15CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020026162-A1 | PROCESS FOR THE MULTISTEP CONTINUOUS-FLOW PREPARATION OF FLIBANSERIN | RICHTER GEDEON NYRT. (HU) | 2020-02-06 | — | — | WO | disclosed |