Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774022 | 0.80 | RAB9A (0.40) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL3138399 | 0.76 | POLB (0.47) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL11568355 | 0.75 | MAPT (0.40) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL12821098 | 0.72 | SIGMAR1 (0.40) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL30309571 | 0.71 | SIGMAR1 (0.39) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL28975392 | 0.71 | SIGMAR1 (0.39) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL28485542 | 0.71 | SIGMAR1 (0.39) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL10687373 | 0.68 | POLB (0.39) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL4101769 | 0.68 | DDB1 (0.46) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL9834330 | 0.67 | KMT2A (0.61) | MEN1KMT2ANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031229-A | SUBSTITUTED IMIDAZOLIDINONE-PENICILLANIC ACIDS, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |