Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748730 | 0.75 | MEN1 (0.48) | MAPTKDM4EGAATDP1SMN1; SMN2 | |
| SCHEMBL7406654 | 0.73 | MAPT (0.44) | MAPTGAALMNASMN1; SMN2KMT2A | |
| SCHEMBL12821098 | 0.72 | SIGMAR1 (0.40) | MAPTKDM4EGAATDP1LMNA | |
| SCHEMBL28485542 | 0.71 | SIGMAR1 (0.39) | MAPTKDM4EGAATDP1LMNA | |
| SCHEMBL28975392 | 0.71 | SIGMAR1 (0.39) | MAPTKDM4EGAATDP1LMNA | |
| SCHEMBL30309571 | 0.71 | SIGMAR1 (0.39) | MAPTKDM4EGAATDP1LMNA | |
| SCHEMBL10687373 | 0.68 | POLB (0.39) | MAPTKDM4EGAATDP1LMNA | |
| SCHEMBL2277437 | 0.67 | SIGMAR1 (0.36) | GAATDP1LMNASIGMAR1NPC1 | |
| SCHEMBL3257577 | 0.66 | SIGMAR1 (0.58) | MAPTKDM4EGAATDP1LMNA | |
| SCHEMBL30728396 | 0.65 | ALDH1A1 (0.33) | MAPTKDM4EGAATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168980-A | SILVER IMIDAZOLINE-2-THIONE | EASTMAN KODAK COMPANY (US) | 1979-09-25 | — | — | US | disclosed |