Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11865224 | 0.99 | KDM4E (0.65) | KDM4EL3MBTL1ALDH1A1HPGDMAOB | |
| SCHEMBL11732688 | 0.96 | KDM4E (0.61) | KDM4EL3MBTL1ALDH1A1HPGDMAOB | |
| Hydrochloric Acid SCHEMBL11871520 | 0.94 | KDM4E (0.59) | KDM4EL3MBTL1ALDH1A1HPGDMAOB | |
| SCHEMBL11868967 | 0.90 | TSHR (0.55) | KDM4EL3MBTL1ALDH1A1MCHR1 | |
| SCHEMBL11870369 | 0.86 | KDM4E (0.51) | KDM4EL3MBTL1ALDH1A1MCHR1 | |
| SCHEMBL11863515 | 0.85 | KMT2A (0.58) | KDM4EL3MBTL1ALDH1A1HPGDKMT2A | |
| SCHEMBL11680146 | 0.85 | KDM4E (0.88) | KDM4EL3MBTL1ALDH1A1HPGDMAOB | |
| Hydrochloric Acid SCHEMBL11678795 | 0.84 | KDM4E (0.86) | KDM4EL3MBTL1ALDH1A1HPGDMAOB | |
| SCHEMBL11677379 | 0.84 | KDM4E (0.86) | KDM4EL3MBTL1ALDH1A1HPGDMAOB | |
| SCHEMBL11859502 | 0.84 | ALDH1A1 (0.62) | KDM4EL3MBTL1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | claimed |
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |