Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11865224 | 0.91 | KDM4E (0.65) | TSHRKDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11748966 | 0.90 | KDM4E (0.67) | KDM4EL3MBTL1ALDH1A1MCHR1 | |
| SCHEMBL11863515 | 0.88 | KMT2A (0.58) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11870369 | 0.86 | KDM4E (0.51) | TSHRKDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11732688 | 0.86 | KDM4E (0.61) | TSHRKDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11750613 | 0.84 | ACHE (0.51) | KDM4EL3MBTL1HRH2HRH1MCHR1 | |
| Hydrochloric Acid SCHEMBL11871520 | 0.84 | KDM4E (0.59) | TSHRKDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11859502 | 0.84 | ALDH1A1 (0.62) | TSHRKDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11676917 | 0.81 | KDM4E (0.65) | TSHRKDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11750568 | 0.78 | L3MBTL1 (0.40) | KDM4EL3MBTL1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |