Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 7/20 | 0.40 |
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572470 | 0.73 | NOS3 (0.55) | GAAMEN1KMT2ALMNANOS3 | |
| SCHEMBL11745466 | 0.72 | NOS3 (0.58) | GAAMEN1KMT2ALMNANOS3 | |
| Hydrochloric Acid SCHEMBL11744315 | 0.70 | NOS3 (0.56) | GAAMEN1KMT2ALMNANOS3 | |
| SCHEMBL28843253 | 0.68 | NOS3 (0.49) | NOS3NOS2MAPTALDH1A1MAOA | |
| SCHEMBL25055314 | 0.68 | NOS3 (0.45) | GAAMEN1KMT2ALMNANOS3 | |
| SCHEMBL11698972 | 0.65 | GAA (0.59) | GAAMEN1KMT2ALMNARAB9A | |
| SCHEMBL9375021 | 0.65 | ALDH1A1 (0.43) | GAAMEN1KMT2ALMNANOS3 | |
| Hydrochloric Acid SCHEMBL9374659 | 0.65 | GRIN2B (0.45) | LMNANOS3NOS2MAPTALDH1A1 | |
| SCHEMBL25446631 | 0.64 | NOS3 (0.47) | NOS3NOS2RAB9ANPC1MAPT | |
| SCHEMBL31135519 | 0.63 | TSHR (0.67) | GAANOS3NOS2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009170-A | 1-Ethoxy-3,4-dihydroisoquindines | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |