SCHEMBL11749641

SCHEMBL11749641

O=C1C=CC(=S)N1C(Cl)(Cl)Cl

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11704366 0.82 MGLL (0.39) MGLLGSK3AGSK3BFAAH
SCHEMBL28185687 0.62
SCHEMBL9863921 0.60
SCHEMBL9774898 0.60 MGLL (0.45) MGLLGSK3AGSK3BFAAH
SCHEMBL152557 0.60 MGLL (0.45) MGLLGSK3AGSK3BFAAH
SCHEMBL3482921 0.60 MGLL (0.38) MGLLGSK3AGSK3BFAAH
SCHEMBL9863926 0.57
SCHEMBL7962613 0.57 MGLL (0.36) MGLLGSK3AGSK3BFAAH
SCHEMBL4307721 0.57
SCHEMBL21419589 0.57 MGLL (0.35) MGLLGSK3AGSK3BFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4012359-A N-TRICHLOROMETHYL-THIOIMIDES, USEFUL IN POLYMERS FERRO CORPORATION (US) 1977-03-15 US disclosed