Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | WRN | Q14191 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509113 | 0.78 | MGLL (0.38) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL18391260 | 0.76 | MGLL (0.36) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL709031 | 0.72 | MGLL (0.41) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL8097847 | 0.72 | MGLL (0.41) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL9774898 | 0.71 | MGLL (0.45) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL152557 | 0.71 | MGLL (0.45) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL24199813 | 0.70 | MGLL (0.35) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL29480092 | 0.70 | MGLL (0.35) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL10037569 | 0.69 | ALDH1A1 (0.35) | MGLLGSK3AGSK3BALDH1A1BLM | |
| SCHEMBL17924837 | 0.68 | MGLL (0.38) | MGLLGSK3AGSK3BALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265509-B1 | POLYVINYL ACETALS | NOVARTIS AG (CH) | 2001-07-24 | — | — | US | disclosed |
| EP-0807265-B1 | CROSSLINKED POLYMERS | NOVARTIS AG (CH) | 2000-04-12 | — | — | EP | disclosed |
| US-5932674-A | MOLDING MATERIALS; CONTACT LENSES | NOVARTIS AG (CH) | 1999-08-03 | — | — | US | disclosed |
| EP-0807265-A1 | CROSSLINKED POLYMERS | Novartis AG (CH) | 1997-11-19 | — | — | EP | disclosed |
| WO-1996024074-A1 | CROSSLINKED POLYMERS | NOVARTIS AG (CH) | 1996-08-08 | — | — | WO | disclosed |