Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749641 | 0.82 | MGLL (0.31) | MGLLGSK3AGSK3BFAAH | |
| SCHEMBL152557 | 0.69 | MGLL (0.45) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL9774898 | 0.69 | MGLL (0.45) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL3482921 | 0.69 | MGLL (0.38) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL7962613 | 0.66 | MGLL (0.36) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL18461453 | 0.65 | MGLL (0.41) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL21419589 | 0.65 | MGLL (0.35) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL21999424 | 0.65 | MGLL (0.41) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL3482352 | 0.65 | MGLL (0.35) | MGLLGSK3AGSK3BFAAHALDH1A1 | |
| SCHEMBL5889438 | 0.65 | MGLL (0.35) | MGLLGSK3AGSK3BFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004627-A | Pneumatic tire with sidewall composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-01-25 | — | — | US | claimed |
| CN-107441506-A | Gene delivery carrier and its preparation and application | 上海交通大学 | 2017-12-08 | — | — | CN | disclosed |
| US-4004627-A | Pneumatic tire with sidewall composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-01-25 | — | — | US | disclosed |