Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | CASP7 | P55210 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742743 | 0.87 | ALDH1A1 (0.49) | CYP1A2CYP2C19ALDH1A1HSD17B10KMT2A | |
| SCHEMBL11745048 | 0.81 | ALDH1A1 (0.55) | CYP1A2ALDH1A1HSD17B10KMT2AHIF1A | |
| SCHEMBL11744997 | 0.80 | NPC1 (0.49) | CYP1A2ALDH1A1HSD17B10KMT2AHIF1A | |
| SCHEMBL11745287 | 0.80 | NPC1 (0.49) | CYP1A2ALDH1A1HSD17B10KMT2AHIF1A | |
| SCHEMBL11749644 | 0.75 | ALDH1A1 (0.44) | CYP1A2ALDH1A1HSD17B10KMT2AHIF1A | |
| SCHEMBL11744427 | 0.73 | PTGES (0.42) | CYP1A2ALDH1A1HSD17B10KMT2AHIF1A | |
| SCHEMBL396506 | 0.72 | MAPT (0.55) | ALDH1A1HSD17B10TP53KDM4EHPGD | |
| SCHEMBL29717679 | 0.72 | MAPT (0.55) | ALDH1A1HSD17B10TP53KDM4EHPGD | |
| SCHEMBL11484277 | 0.71 | KDM4E (0.54) | ALDH1A1HSD17B10TP53KDM4EHPGD | |
| SCHEMBL11483878 | 0.71 | KDM4E (0.54) | ALDH1A1HSD17B10TP53KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008232-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-3979516-A | Anti-inflammatory 3-amino-5,6-diaryl-1,2,4-triazines | ELI LILLY AND COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3948894-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1976-04-06 | — | — | US | disclosed |