SCHEMBL11751985

SCHEMBL11751985

O=C(CCCCN1CCCCC1)c1ccc2c(c1)Cc1cc(C(=O)CCCCN3CCCCC3)ccc1O2

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
ALDH1A1 P00352 6/20 0.56
MAOB P27338 3/20 0.56
HPGD P15428 1/20 0.56
MAPT P10636 1/20 0.55
HSD17B10 Q99714 1/20 0.55
NPC1 O15118 1/20 0.51
TP53 P04637 1/20 0.51
RAB9A P51151 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
KMT2A Q03164 3/20 0.46
MCHR1 Q99705 1/20 0.45
GFER P55789 1/20 0.45
HRH3 Q9Y5N1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11729199 0.96 L3MBTL1 (0.61) KDM4EL3MBTL1ALDH1A1MAOBHPGD
SCHEMBL11794977 0.95 L3MBTL1 (0.59) KDM4EL3MBTL1ALDH1A1MAOBHPGD
SCHEMBL11795205 0.86 TSHR (0.60) KDM4EL3MBTL1ALDH1A1MAOBHPGD
SCHEMBL11680146 0.85 KDM4E (0.88) KDM4EL3MBTL1ALDH1A1MAOBHPGD
SCHEMBL11748266 0.85 KDM4E (0.55) KDM4EL3MBTL1ALDH1A1MAOBHPGD
SCHEMBL11797482 0.85 ALDH1A1 (0.71) KDM4EL3MBTL1ALDH1A1MAPTHSD17B10
Hydrochloric Acid SCHEMBL11678795 0.84 KDM4E (0.86) KDM4EL3MBTL1ALDH1A1MAOBHPGD
SCHEMBL11677379 0.84 KDM4E (0.86) KDM4EL3MBTL1ALDH1A1MAOBHPGD
SCHEMBL11803305 0.84 MAOB (0.64) KDM4EL3MBTL1ALDH1A1MAOBHPGD
Hydrochloric Acid SCHEMBL11748357 0.83 MAOB (0.65) KDM4EL3MBTL1ALDH1A1MAOBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4041165-A TREATING DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1977-08-09 US disclosed
US-3957989-A ADMINISTERING RICHARDSON-MERRELL INC. (US) 1976-05-18 US disclosed
US-3937833-A DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1976-02-10 US disclosed