Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 7/20 | 0.59 |
| ▸ | PPARA | Q07869 | 7/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754185 | 1.00 | PPARD (0.61) | PPARDPPARGPPARAPTGDR2PTGS2 | |
| SCHEMBL10801302 | 0.94 | PPARD (0.61) | PPARDPPARGPPARAPTGDR2PTGS2 | |
| SCHEMBL11041560 | 0.92 | PPARD (0.49) | PPARDPPARGPPARAPTGDR2POLB | |
| SCHEMBL11754768 | 0.91 | PPARD (0.58) | PPARDPPARGPPARAPTGDR2PTGS2 | |
| SCHEMBL11752001 | 0.91 | PPARD (0.58) | PPARDPPARGPPARAPTGDR2PTGS2 | |
| SCHEMBL11754318 | 0.88 | PPARD (0.48) | PPARDPPARGPPARAPTGDR2PTGS2 | |
| SCHEMBL11749416 | 0.88 | PTGDR2 (0.50) | PPARDPPARGPPARAPTGDR2PTGS2 | |
| SCHEMBL11753193 | 0.88 | PTGDR2 (0.50) | PPARDPPARGPPARAPTGDR2PTGS2 | |
| SCHEMBL11753168 | 0.87 | PPARD (0.46) | PPARDPPARGPPARAPTGDR2 | |
| SCHEMBL11753504 | 0.87 | PPARD (0.46) | PPARDPPARGPPARAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |