Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | ELANE | P08246 | 4/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | PLAU | P00749 | 3/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757231 | 0.81 | ELANE (0.57) | MAPTELANEF2PLAUCTRB1 | |
| SCHEMBL11752052 | 0.80 | ADORA2A (0.46) | ELANEPOLBSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL15081336 | 0.77 | ELANE (0.58) | MAPTELANEF2PLAUCTRB1 | |
| SCHEMBL11751783 | 0.77 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL11752876 | 0.76 | TSHR (0.47) | MAPTELANEF2PLAUPOLB | |
| SCHEMBL11814240 | 0.76 | L3MBTL1 (0.52) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL15081337 | 0.75 | ELANE (0.56) | MAPTELANEF2PLAUCTRB1 | |
| SCHEMBL11754684 | 0.73 | ABCB1 (0.47) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11748058 | 0.72 | IDE (0.47) | MAPTELANEPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL15081319 | 0.71 | ELANE (0.53) | MAPTELANEF2PLAUCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |