Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748058 | 0.89 | IDE (0.47) | ADORA2AELANEALDH1A1TSHRMAPK1 | |
| SCHEMBL11751783 | 0.81 | MAPT (0.42) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL11752876 | 0.80 | TSHR (0.47) | ELANEALDH1A1TSHRMAPK1KMT2A | |
| SCHEMBL11752029 | 0.80 | MAPT (0.51) | ELANEALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11756528 | 0.79 | ALDH1A1 (0.45) | ADORA2AALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL11755931 | 0.78 | ELANE (0.51) | ADORA2AELANEALDH1A1TSHRMAPK1 | |
| SCHEMBL11754684 | 0.77 | ABCB1 (0.47) | ALDH1A1MAPK1MEN1KMT2AHPGD | |
| SCHEMBL11751308 | 0.76 | ADORA2A (0.49) | ADORA2AELANEALDH1A1TSHRMAPK1 | |
| SCHEMBL11747559 | 0.75 | KMT2A (0.42) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL17683271 | 0.74 | ELANE (0.52) | ELANEALDH1A1TSHRMAPK10MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | claimed |