Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42490 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL29172696 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL10822622 | 0.93 | — | — | |
| Ethylene SCHEMBL28794343 | 0.88 | TSHR (0.46) | — | |
| Isopropylamine SCHEMBL910714 | 0.88 | ALDH1A1 (0.42) | — | |
| Ethylenediamine SCHEMBL1929817 | 0.83 | GABRR1 (0.42) | — | |
| Ethylenediamine SCHEMBL1929819 | 0.83 | GABRR1 (0.42) | — | |
| Methanesulfonamide SCHEMBL4590913 | 0.81 | CA1 (0.40) | — | |
| SCHEMBL578763 | 0.77 | MMP8 (0.39) | — | |
| SCHEMBL7525656 | 0.76 | CYP2D6 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051252-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |