Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.40 |
| ▸ | CA2 | P00918 | 9/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42490 | 0.84 | — | — | |
| Isopropylamine SCHEMBL910714 | 0.81 | ALDH1A1 (0.42) | CA1CA2CA12CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10822622 | 0.81 | — | — | |
| Ammonia Solution, Strong SCHEMBL29172696 | 0.81 | — | — | |
| Bromide SCHEMBL11752199 | 0.81 | — | — | |
| Ethylenediamine SCHEMBL1929817 | 0.77 | GABRR1 (0.42) | CA1CA2CA12CA9ALDH1A1 | |
| Ethylenediamine SCHEMBL1929819 | 0.77 | GABRR1 (0.42) | CA1CA2CA12CA9ALDH1A1 | |
| Ethylene SCHEMBL28794343 | 0.76 | TSHR (0.46) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL3657986 | 0.75 | CA2 (0.34) | CA1CA2CA12CA9GAA | |
| SCHEMBL1756725 | 0.72 | CYP2D6 (0.33) | CA2ALDH1A1GAACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008082725-A1 | PYRIDAZINONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. (US) | 2008-07-10 | — | — | WO | disclosed |