Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5252883 | 0.98 | MAPT (0.53) | MAPTKMT2ACHRM3KCNH2CHRM2 | |
| SCHEMBL2202827 | 0.89 | CHRM3 (0.47) | MAPTKMT2ACHRM3KCNH2CHRM2 | |
| SCHEMBL9295790 | 0.84 | CHRM3 (0.59) | MAPTKMT2ACHRM3KCNH2CHRM2 | |
| SCHEMBL20607354 | 0.83 | OPRM1 (0.66) | MAPTKMT2ACHRM3KCNH2CHRM2 | |
| SCHEMBL27455034 | 0.83 | KCNN4 (0.59) | MAPTKMT2ACHRM3KCNH2CHRM2 | |
| SCHEMBL9989231 | 0.83 | CHRM3 (0.42) | MAPTKMT2ACHRM3KCNH2CHRM2 | |
| SCHEMBL11752498 | 0.83 | CHRM2 (0.51) | MAPTKMT2ACHRM3KCNH2CHRM2 | |
| SCHEMBL396913 | 0.83 | CHRM2 (0.51) | MAPTKMT2ACHRM3KCNH2CHRM2 | |
| SCHEMBL2201632 | 0.82 | KDM4E (0.43) | MAPTKMT2ACHRM3KCNH2CHRM2 | |
| SCHEMBL2984162 | 0.81 | CHRM3 (0.56) | MAPTKMT2ACHRM3KCNH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103880751-A | Preparation method of imidafenacin | TIANJIN INST PHARM RESEARCH | 2014-06-25 | — | — | CN | claimed |
| CN-103772286-A | Method for preparing imidafenacin | JIANGXI QINGFENG PHARMACEUTICAL CO LTD | 2014-05-07 | — | — | CN | claimed |
| CN-103351344-A | Novel preparation method of imidafenacin intermediate and refined product thereof | BEIJING WANQUAN DEZHONG MEDICAL BIOLOG TECHNOLOGY CO LTD | 2013-10-16 | — | — | CN | claimed |
| CN-103319411-A | Preparation method of imidafenacin | SHAANXI BUCHANG GAOXIN PHARMACEUTICAL CO LTD | 2013-09-25 | — | — | CN | claimed |
| CN-103274983-A | Pyrrole derivatives and preparation method thereof | ZHU XUEQI | 2013-09-04 | — | — | CN | claimed |
| CN-103275036-A | Piperidine derivatives and preparation method thereof | ZHU XUEQI | 2013-09-04 | — | — | CN | claimed |
| CN-103275007-A | Pyrazole derivatives and preparation method thereof | ZHU XUEQI | 2013-09-04 | — | — | CN | claimed |
| CN-103265542-A | Purine derivative and preparation method thereof | ZHU XUEQI | 2013-08-28 | — | — | CN | claimed |
| CN-103254155-A | Tetrahydropyrrole derivative and preparation method thereof | ZHU XUEQI | 2013-08-21 | — | — | CN | claimed |
| CN-103242230-A | Quinolinone derivative and preparation method thereof | BUCHANG GAOXIN PHARMACEUTICAL CO LTD | 2013-08-14 | — | — | CN | claimed |
| CN-101362721-A | Preparation method of 4-(2-methyl-1-imidazolyl)-2-diphenyl butyric acid amide | UNIV SHANXI (CN) | 2009-02-11 | — | — | CN | claimed |
| EP-1907359-A2 | 3,5-SUBSTITUTED PIPERIDINE DERIVATIVES EFFECTIVE ON RENIN-RELATED DISORDERS | Novartis AG (CH) | 2008-04-09 | — | — | EP | claimed |
| CN-101076521-A | Process for producing muscarine receptor antagonist and intermediate therefor | KYORIN SEIYAKU KK (JP) | 2007-11-21 | — | — | CN | claimed |
| WO-2007006534-A2 | PIPERIDINE DERIVATIVES USEFUL IN THE DIAGNOSTIC AND THERAPEUTIC TREATMENT OF DISEASES DEPENDING ON RENIN ACTIVITY | NOVARTIS AG (CH) | 2007-01-18 | — | — | WO | claimed |
| CN-1842333-A | Sustained release tablet for oral use | KYORIN SEIYAKU KK (JP) | 2006-10-04 | — | — | CN | claimed |
| CN-1681789-A | 1-pyridin-4-yl-urea derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2005-10-12 | — | — | CN | claimed |
| US-20040034104-A1 | 2,2-Diphenylbutanamide derivatives and medicines containing the same | SSP CO., LTD. (JP) | 2004-02-19 | — | — | US | claimed |
| CN-1469862-A | 2, 2-diphenylbutanamide derivatives and drugs containing the same | SS制药株式会社 | 2004-01-21 | — | — | CN | claimed |
| EP-1325912-A1 | 2,2-DIPHENYLBUTANAMIDE DERIVATIVES AND MEDICINES CONTAINING THE SAME | SSP Co., Ltd. (JP) | 2003-07-09 | — | — | EP | claimed |
| CN-1270582-A | Imidazoline compounds | MITSUBISHI PHARMACEUTICAL CO L (JP) | 2000-10-18 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034104-A1 | 2,2-Diphenylbutanamide derivatives and medicines containing the same | OPRD1, OPRM1, OPRK1 | MAPT 2582/4885KMT2A 1632/4885CHRM3 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.