Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253643 | 0.85 | CYP2C19 (0.49) | CHRM2CHRM1CHRM3OPRM1DRD3 | |
| SCHEMBL28443220 | 0.81 | OPRM1 (0.43) | OPRM1DRD3DRD2DRD4CYP2B6 | |
| SCHEMBL26914645 | 0.81 | KMT2A (0.42) | CHRM2CHRM1CHRM3OPRM1DRD3 | |
| SCHEMBL11752498 | 0.79 | CHRM2 (0.51) | CHRM2CHRM1CHRM3OPRM1DRD3 | |
| SCHEMBL396913 | 0.79 | CHRM2 (0.51) | CHRM2CHRM1CHRM3OPRM1DRD3 | |
| SCHEMBL20607354 | 0.76 | OPRM1 (0.66) | CHRM2CHRM1CHRM3OPRM1DRD3 | |
| SCHEMBL4030430 | 0.76 | MAPT (0.55) | CHRM2CHRM1CHRM3OPRM1DRD3 | |
| Hydrochloric Acid SCHEMBL5252883 | 0.74 | MAPT (0.53) | CHRM2CHRM1CHRM3OPRM1DRD3 | |
| SCHEMBL9359426 | 0.74 | KMT2A (0.44) | CYP2C19HIF1AKMT2AMAPTTSHR | |
| SCHEMBL5071313 | 0.74 | KMT2A (0.57) | CYP2C19HIF1AKMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6287490-B2 | Preparing a mold, filling the mold cavity with a fiber reinforced copolymerizable material comprising an organic matrix and a fiber component embedded within the matrix, pressurizing and curing the reiforced polymerizable material | IVOCLAR AG (LI) | 2001-09-11 | — | — | US | disclosed |
| US-20010001510-A1 | METHOD FOR MANUFACTURING A DENTAL PROSTHESIS | IVOCLAR AG (LI) | 2001-05-24 | — | — | US | disclosed |
| US-6010337-A | Dental prosthesis with composite support shell and coating, preimpregnated fabric part, manufacturing method and machine | BILLET GILLES (FR) | 2000-01-04 | — | — | US | disclosed |
| US-5951293-A | Dental prosthesis with composite support shell and coating, preimpregnated fabric part, manufacturing method and machine | BILLET GILLES (FR) | 1999-09-14 | — | — | US | disclosed |
| US-5947737-A | Dental prosthesis with composite support shell and coating, preimpregnated fabric part, manufacturing method and machine | BILLET GILLES (FR) | 1999-09-07 | — | — | US | disclosed |
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |
| US-5839900-A | Dental prosthesis with composite support shell and coating, preimpregnated fabric part, manufacturing method and machine | BILLET GILLES (FR) | 1998-11-24 | — | — | US | disclosed |
| EP-0872218-A2 | Method for manufacturing a dental prosthesis | IVOCLAR AG (LI) | 1998-10-21 | — | — | EP | disclosed |