Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761094 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL6072946 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3050298 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL8348104 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL1302931 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL17101325 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL219171 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL865783 | 0.88 | — | — | |
| SCHEMBL148513 | 0.88 | — | — | |
| SCHEMBL17101240 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046893-A | ANALGESIC, ANTIPHLOGISTIC | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JA) | 1977-09-06 | — | — | US | disclosed |
| US-3946012-A | 6-L-dihydroxyethyl-2,4,7-trioxo-8-D-ribityl pteridine and process for producing the same | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JA) | 1976-03-23 | — | — | US | disclosed |