SCHEMBL6072946

SCHEMBL6072946

[CH2]C(O)C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.71
LMNA P02545 2/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
KDM4E B2RXH2 2/20 0.44
PDE4A P27815 1/20 0.44
USP2 O75604 1/20 0.41
SLCO1B1 Q9Y6L6 1/20 0.41
MGAM O43451 5/20 0.33
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TOP1 P11387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3761094 1.00 TDP1 (0.71) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL11753239 1.00 TDP1 (0.71) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL3050298 0.97 LMNA (0.69) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL8348104 0.97 LMNA (0.69) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL1302931 0.97 LMNA (0.69) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL17101325 0.97 LMNA (0.69) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL219171 0.97 LMNA (0.69) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL865783 0.88
SCHEMBL148513 0.88
SCHEMBL17101240 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180344648-A1 CLOBAZAM TABLET FORMULATION AND PROCESS FOR ITS PREPARATION Piramal Enterprises Limited (IN) 2018-12-06 US claimed
WO-2006014409-A1 METHOD OF TREATING ANIMAL’S EXTERIOR FOR CLEANING AND/OR INSECT REPELLENCY ACHTMANN HANS (US) 2006-02-09 WO disclosed
EP-0231714-A1 Nematicide and insecticide compositions containing heterocyclic compounds RHONE-POULENC AGROCHIMIE (FR) 1987-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180344648-A1 CLOBAZAM TABLET FORMULATION AND PROCESS FOR ITS PREPARATION SI, SLC6A13, SLC6A11 TDP1 3667/4885LMNA 3037/4885L3MBTL1 4304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.