SCHEMBL219171

SCHEMBL219171

[CH2]C(O)C(O)C(O)C(O)CO

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
TDP1 Q9NUW8 1/20 0.65
KDM4E B2RXH2 2/20 0.46
PDE4A P27815 1/20 0.46
USP2 O75604 1/20 0.42
SLCO1B1 Q9Y6L6 1/20 0.42
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
TOP1 P11387 1/20 0.32
MGAM O43451 3/20 0.31
SI P14410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17101325 1.00 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL1302931 1.00 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL8348104 1.00 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL3050298 1.00 LMNA (0.69) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL11753239 0.97 TDP1 (0.71) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL3761094 0.97 TDP1 (0.71) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL6072946 0.97 TDP1 (0.71) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL865783 0.90
SCHEMBL148513 0.90
SCHEMBL17101240 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 659 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118317790-A Pharmaceutical composition comprising p-borophenylalanine 腾博龙公司 2024-07-09 CN claimed
WO-2023111396-A1 PHARMACEUTICAL COMPOSITION COMPRISING P-BORONOPHENYLALANINE TENBORON OY (FI) 2023-06-22 WO claimed
CN-108135897-B Fused benzamides 勃林格殷格翰国际有限公司 2021-07-27 CN claimed
CN-108473756-B Polycarbonate resin composition, molded article, and carrier tape 住化PC有限公司 2020-07-24 CN claimed
EP-3337483-B1 NOVEL ANNELATED BENZAMIDES BOEHRINGER INGELHEIM INT (DE) 2019-10-09 EP claimed
EP-2974713-B1 CERAMIDE-LIKE FUNCTION IMPARTING AGENT KAO CORP (JP) 2019-05-01 EP claimed
EP-3229591-B1 SUGAR SURFACTANTS AND USE THEREOF IN AGROCHEMICAL COMPOSITIONS CLARIANT INT LTD (CH) 2018-10-03 EP claimed
EP-2872480-B1 LIPASE-STABLE THICKENING AGENT EVONIK DEGUSSA GMBH (DE) 2018-09-26 EP claimed
US-20180186774-A1 NOVEL ANNELATED BENZAMIDES BOEHRINGER INGELHEIM INT (DE) 2018-07-05 US claimed
EP-3337483-A1 NOVEL ANNELATED BENZAMIDES Boehringer Ingelheim International GmbH (DE) 2018-06-27 EP claimed
EP-0998946-A1 Non-porphyrin compound for use as a diagnosticum and/or pharmaceutical K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) 2000-05-10 EP claimed
WO-2000009169-A1 NON-PORPHYRIN COMPOUND FOR USE AS A DIAGNOSTICUM AND/OR PHARMACEUTICAL K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) 2000-02-24 WO claimed
EP-0767781-B1 NOVEL QUATERNARY AMMONIUM DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF AS SURFACTANTS SEPPIC SA (FR) 1999-03-31 EP claimed
US-5756066-A Iodine-containing peptides SCHERING AKTIENGESELLSCHAFT (DE) 1998-05-26 US claimed
US-5674467-A USED IN NMR DIAGNOSIS, RADIODIAGNOSIS OR RADIOTHERAPY INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) 1997-10-07 US claimed
US-5508454-A FOR BIOCOMPATIBLE CLEANING COMPOUNDS, CONDITIONERS, EMULSIFIERS OR FOAMS USEFUL IN COSMETIC OR DRUG DELIVERY MIXTURES SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES -SEPPIC (FR) 1996-04-16 US claimed
US-5446027-A Moisturizers improving skin roughness KAO CORPORATION (JP) 1995-08-29 US claimed
EP-0596450-A1 Amide derivative and external skin care preparation containing the same KAO CORPORATION (JP) 1994-05-11 EP claimed
EP-0368763-B1 4-MERCAPTO BUTYRAMIDES N-MONO OR N,N-DISUBSTITUTED BY A MONO OR POLYHYDROXYALKYL RADICAL, AND THEIR USE AS REDUCING AGENTS IN THE PROCESS OF PERMANENT DEFORMATION OF THE HAIR L'OREAL (FR) 1992-10-14 EP claimed
WO-1982002889-A1 AMMONIUM SALTS OF A SUBSTITUTED CARBONIC ACID,PREPARATION METHOD THEREOF,UTILIZATION AND MEDICINAL PREPARATIONS CONTAINING THEM CIBA GEIGY AG (CH) 1982-09-02 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180186774-A1 NOVEL ANNELATED BENZAMIDES HDAC10, HDAC11, H1-0 LMNA 3647/4885L3MBTL1 2738/4885TDP1 2896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.