SCHEMBL11754451

SCHEMBL11754451

O=C1CCCC(=O)N1c1cc(Cl)cc(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
LMNA P02545 1/20 0.55
KMT2A Q03164 4/20 0.50
TSHR P16473 2/20 0.47
HSD17B10 Q99714 2/20 0.40
USP2 O75604 1/20 0.40
BCL2A1 Q16548 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 2/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
ADRB1 P08588 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethachlon SCHEMBL410360 0.91 TSHR (0.50) ALDH1A1LMNAKMT2ATSHRHSD17B10
SCHEMBL10268369 0.81 ALDH1A1 (0.50) ALDH1A1KMT2ATSHRHSD17B10USP2
SCHEMBL6140503 0.80 LMNA (0.79) ALDH1A1LMNAKMT2ATSHRHSD17B10
SCHEMBL6140528 0.79 KMT2A (0.62) ALDH1A1LMNAKMT2ATSHRL3MBTL1
SCHEMBL11753467 0.76 KMT2A (0.48) ALDH1A1LMNAKMT2AL3MBTL1MEN1
SCHEMBL11755191 0.76 KMT2A (0.48) ALDH1A1LMNAKMT2AL3MBTL1MEN1
SCHEMBL8299106 0.76 KMT2A (0.55) ALDH1A1LMNAKMT2ATSHRHSD17B10
SCHEMBL7819571 0.74 LMNA (0.51) ALDH1A1LMNAKMT2ATSHRHSD17B10
Dimethachlon SCHEMBL28267717 0.72 TSHR (0.50) ALDH1A1LMNAKMT2ATSHRHSD17B10
SCHEMBL1361674 0.71 L3MBTL1 (0.41) ALDH1A1LMNAKMT2ATSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1943342-A Control agent for plant botrytis and sclerotium and preparing method UNIV DALIAN (CN) 2007-04-11 CN disclosed
US-4009278-A Antimicrobial composition and method containing N-(3,5-dihalophenyl)-imide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-02-22 US disclosed