Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752319 | 0.94 | NOX1 (0.48) | MAPK14MAPTSMN1; SMN2NOX1ALDH1A1 | |
| SCHEMBL11749619 | 0.94 | NOX1 (0.48) | MAPK14MAPTSMN1; SMN2NOX1ALDH1A1 | |
| SCHEMBL11754011 | 0.92 | APP (0.40) | MAPK14APPMAPTALDH1A1HSD17B10 | |
| SCHEMBL11755414 | 0.92 | APP (0.40) | MAPK14APPMAPTALDH1A1HSD17B10 | |
| SCHEMBL11749454 | 0.83 | RXRA (0.44) | MAPTSMN1; SMN2NOX1ALDH1A1HSD17B10 | |
| SCHEMBL11750003 | 0.82 | ALDH1A1 (0.38) | MAPTSMN1; SMN2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11752407 | 0.81 | NR4A2 (0.48) | MAPTSMN1; SMN2NOX1ALDH1A1HSD17B10 | |
| SCHEMBL11755115 | 0.80 | RXRA (0.46) | MAPK14MAPTSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL11758179 | 0.79 | MAPK14 (0.41) | MAPK14APPMAPTSMN1; SMN2NOX1 | |
| SCHEMBL11751140 | 0.77 | KMT2A (0.40) | MAPTSMN1; SMN2ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |