Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8880119 | 0.87 | AKR1B1 (0.66) | AKR1B1MAPK14TTRACHENOTUM | |
| SCHEMBL11663201 | 0.83 | AKR1B1 (0.61) | AKR1B1MAPK14TTRACHENOTUM | |
| SCHEMBL11569877 | 0.83 | AKR1B1 (0.61) | AKR1B1MAPK14TTRACHENOTUM | |
| SCHEMBL11562156 | 0.80 | AKR1B1 (0.65) | AKR1B1MAPK14TTRSRD5A2RAB9A | |
| SCHEMBL2007673 | 0.80 | AKR1B1 (0.57) | AKR1B1MAPK14PTPRC | |
| SCHEMBL11566471 | 0.80 | AKR1B1 (0.60) | AKR1B1MAPK14TTRACHENOTUM | |
| SCHEMBL11565479 | 0.77 | AKR1B1 (0.54) | AKR1B1MAPK14TTRACHENOTUM | |
| SCHEMBL11567137 | 0.76 | AKR1B1 (0.56) | AKR1B1MAPK14TTRACHENOTUM | |
| SCHEMBL11832932 | 0.76 | AKR1B1 (0.53) | AKR1B1MAPK14TTRACHENOTUM | |
| SCHEMBL11564660 | 0.76 | AKR1B1 (0.56) | AKR1B1MAPK14TTRACHENOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055574-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, MUSCLE RELAXANT | SYNTEX (U.S.A.) INC. (US) | 1977-10-25 | — | — | US | disclosed |