Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HK2 | P52789 | 5/20 | 0.34 |
| ▸ | HK1 | P19367 | 4/20 | 0.34 |
| ▸ | PYGB | P11216 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415331 | 0.87 | LMNA (0.50) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL11415353 | 0.87 | LMNA (0.50) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL13382478 | 0.78 | LMNA (0.50) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL31105669 | 0.75 | MAPK1 (0.48) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL18849204 | 0.75 | MAPK1 (0.48) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL11777948 | 0.72 | LMNA (0.50) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL11756125 | 0.70 | CA2 (0.49) | PYGBCA1CA2CA9 | |
| SCHEMBL11758775 | 0.70 | CA2 (0.49) | PYGBCA1CA2CA9 | |
| SCHEMBL23705263 | 0.70 | KDM4E (0.37) | LMNAKDM4ECYP2D6CYP2C19HK2 | |
| SCHEMBL24256228 | 0.70 | KDM4E (0.37) | LMNAKDM4ECYP2D6CYP2C19HK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4057684-A | ANTITUMOR | TOKYO TANABE COMPANY, LIMITED (JA) | 1977-11-08 | — | — | US | disclosed |