Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HK1 | P19367 | 4/20 | 0.32 |
| ▸ | HK2 | P52789 | 4/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorozotocin SCHEMBL8539 | 0.89 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL1648834 | 0.89 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL11409484 | 0.89 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL11409480 | 0.89 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL19520816 | 0.88 | LMNA (0.63) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| Chlorozotocin SCHEMBL10424026 | 0.82 | LMNA (0.78) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| SCHEMBL13382542 | 0.81 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19HK1 | |
| SCHEMBL11573190 | 0.80 | LMNA (0.52) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| SCHEMBL29572633 | 0.80 | LMNA (0.52) | LMNAKDM4ECYP2D6CYP2C19ADRA2A | |
| SCHEMBL11573181 | 0.80 | LMNA (0.52) | LMNAKDM4ECYP2D6CYP2C19ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4057684-A | ANTITUMOR | TOKYO TANABE COMPANY, LIMITED (JA) | 1977-11-08 | — | — | US | disclosed |