Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615110 | 0.88 | NPC1 (0.54) | NPC1RAB9AKDM4EPABPC1APOBEC3A | |
| SCHEMBL176660 | 0.87 | SIRT2 (0.66) | NPC1RAB9AKDM4EPABPC1APOBEC3A | |
| Hydrochloric Acid SCHEMBL9615105 | 0.87 | KDM4E (0.53) | NPC1RAB9AKDM4EPABPC1APOBEC3A | |
| SCHEMBL278343 | 0.76 | PGR (0.66) | MAOAMAOBCNR2PGRRORA | |
| SCHEMBL6774209 | 0.74 | PGR (0.64) | MAOAMAOBCNR2PGRRORA | |
| SCHEMBL6278388 | 0.74 | PGR (0.64) | MAOAMAOBCNR2PGRRORA | |
| SCHEMBL6575875 | 0.74 | PGR (0.64) | MAOAMAOBCNR2PGRRORA | |
| SCHEMBL750975 | 0.74 | PGR (0.64) | MAOAMAOBCNR2PGRRORA | |
| SCHEMBL1001993 | 0.74 | PGR (0.64) | MAOAMAOBCNR2PGRRORA | |
| SCHEMBL6275417 | 0.74 | PGR (0.64) | MAOAMAOBCNR2PGRRORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006164-A | TRANQUILIZER | PFIZER INC. (US) | 1977-02-01 | — | — | US | disclosed |
| US-4006164-A | TRANQUILIZER | PFIZER INC. (US) | 1977-02-01 | — | — | US | disclosed |
| US-4006164-A | TRANQUILIZER | PFIZER INC. (US) | 1977-02-01 | — | — | US | disclosed |
| US-3968231-A | 4-Aryl-1,2,3,4-tetrahydropyrrolo(3,4-b)indoles for treating schizophrenic manifestations | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |
| US-3968231-A | 4-Aryl-1,2,3,4-tetrahydropyrrolo(3,4-b)indoles for treating schizophrenic manifestations | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |
| US-3968231-A | 4-Aryl-1,2,3,4-tetrahydropyrrolo(3,4-b)indoles for treating schizophrenic manifestations | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |
| US-3925409-A | 4-Aryl-1,2,3,4-tetrahydropyrrolo{8 3,4-b{9 indoles | PFIZER | 1975-12-09 | — | — | US | disclosed |