SCHEMBL6575875

SCHEMBL6575875

CCCCCCCCCCCCCCCCn1c2ccccc2c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.64
RORA P35398 1/20 0.64
RORC P51449 1/20 0.64
RORB Q92753 1/20 0.64
MAOA P21397 11/20 0.60
MAOB P27338 11/20 0.60
GRIN1 Q05586 9/20 0.60
GRIN2A Q12879 9/20 0.60
GRIN2B Q13224 9/20 0.60
ACHE P22303 3/20 0.60
CNR2 P34972 1/20 0.60
PSEN1 P49768 3/20 0.59
PSEN2 P49810 3/20 0.59
APH1B Q8WW43 3/20 0.59
NCSTN Q92542 3/20 0.59
APH1A Q96BI3 3/20 0.59
PSENEN Q9NZ42 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29311733 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL5153894 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL29490761 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL6275417 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL6774209 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL6278388 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL1000878 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL1001993 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL750975 1.00 PGR (0.64) PGRRORARORCRORBMAOA
SCHEMBL29557199 1.00 PGR (0.64) PGRRORARORCRORBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113307953-B Solid-phase polycarbazole derivative electroluminescence system and construction method and application thereof 齐鲁工业大学 2022-07-22 CN disclosed
CN-110003089-B 3-hydroxymethyl-9-substituted carbazole and preparation method thereof 陕西科技大学 2022-07-01 CN disclosed
CN-113307953-A Solid-phase polycarbazole derivative electroluminescent system and construction method and application thereof 齐鲁工业大学 2021-08-27 CN disclosed
US-20150273457-A1 HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS NATIONAL SCIENCE FOUNDATION 2015-10-01 US disclosed
US-8993804-B2 Highly active multidentate catalysts for efficient alkyne metathesis THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2015-03-31 US disclosed
US-20130261295-A1 Highly Active Multidentate Catalysts for Efficient Alkyne Metathesis THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2013-10-03 US disclosed
EP-1453802-A1 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF THE UNIVERSITY OF SHEFFIELD (GB) 2004-09-08 EP disclosed
WO-2003050086-A1 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF THE UNIVERSITY OF SHEFFIELD (GB) 2003-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150273457-A1 HIGHLY ACTIVE MULTIDENTATE CATALYSTS FOR EFFICIENT ALKYNE METATHESIS PCNA, TRIM58, CAD PGR 4605/4885RORA 4785/4885RORC 4704/4885
US-20130261295-A1 Highly Active Multidentate Catalysts for Efficient Alkyne Metathesis PCNA, TRIM58, CAD PGR 4605/4885RORA 4785/4885RORC 4704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.